Cellular reprogramming technology is over 50 years old. Its main goal is to rejuvenate mature, specialized somatic cells (cells that make up the body, except for the germline cells that produce eggs and sperm), turning them into pluripotent cells, which can develop into all cells of the adult body. This can be achieved by erasing the somatic cell's epigenetic memories. Pluripotency can be induced using a “cocktail” of transcription factors, the final product of such procedure being iPS cells (induced pluripotent stem cells)., whose discovery is expected to contribute to various areas of science, technology and industry.
In this section, I will elaborate on the concepts outlined above, giving you an overview on how the field of cellular reprogramming emerged and developed to its current size and status.
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